-
TurboMice™ fast homozygous mouse customization
A cell is said to be homozygous for a particular gene when identical alleles of the gene are present on both homologous chromosomes.
-
TurboMice™ fast gene-edited humanized mouse customization
Humanized mouse models have a wide range of applications in the research fields of AIDS, cancer, infectious disease, and blood disease.
-
TurboMice™ fast KI mouse customization
Knock-in (KI) is a technique that utilizes homologous recombination of genes to transfer an exogenous functional gene into a homologous sequence in the cell and genome, and obtain expression well in the cell after gene recombination.
-
TurboMice™ fast CKO mouse customization
Conditional Knock-out (CKO) is a tissue-specific gene knockout technology achieved by a localized recombination system.
-
TurboMice™ multi-locus gene-edited mouse customization
By applying TurboMice™ technology, we can directly screen embryonic stem cells after gene editing in 3-5 days, then construct a tetraploid cell, and get homozygous multi-locus gene-edited mice in 3-5 months after surrogacy by mother mice, which can save 1 year for our clients.
-
TurboMice™ long fragment gene-edited mouse customization
TurboMice™ technology enables precise gene editing of long fragments over 20kb, thereby facilitating the rapid production of complex models such as humanization, conditional knockout (CKO), and large fragment knock-in (KI).